Advanced Oncology Certified Nurse Practitioner (AOCNP) Certification Practice Test

Epstein-Barr virus (EBV) is most commonly associated with Hodgkin lymphoma, which is a type of cancer that originates in the lymphatic system, specifically from a type of white blood cell known as lymphocytes. The association between EBV and Hodgkin lymphoma is well-established; studies have shown that a significant percentage of Hodgkin lymphoma cases contain EBV-related sequences within the cancer cells. This connection is thought to arise due to EBV’s ability to manipulate the immune response and promote cellular proliferation, ultimately contributing to the development of the cancer.

In contrast, while EBV has been implicated in other malignancies, such as nasopharyngeal carcinoma and certain types of non-Hodgkin lymphomas, it is not typically linked to breast cancer, lung cancer, or conditions like pancytopenia, which is a reduction in red blood cells, white blood cells, and platelets in the blood rather than a cancer diagnosis. Understanding the specific viral associations with different cancers is crucial for appropriate diagnosis and treatment in oncology nursing practice.