Advanced Oncology Certified Nurse Practitioner (AOCNP) Certification Practice Test

What does the MASCC risk index quantify to predict progression to sepsis?

1. Complete blood count results

2. Age, systolic BP, hydration status

3. Presence of fever and chills

4. Type of tumor only

The correct answer is: Age, systolic BP, hydration status

The MASCC (Multinational Association for Supportive Care in Cancer) risk index is a clinical tool designed to help assess the risk of complications, particularly sepsis, in patients undergoing chemotherapy and experiencing febrile neutropenia. The index takes into account several clinical factors that are significant predictors of the severity of infection and the likelihood of progression to sepsis. The correct option emphasizes age, systolic blood pressure, and hydration status, all of which are crucial in determining the overall clinical condition of a patient. - **Age** is a recognized risk factor since older patients may have a compromised immune system and underlying comorbidities that can affect their response to infections. - **Systolic blood pressure** serves as a vital sign indicator; hypotension can suggest fluid loss, septic shock, or other critical conditions, thereby indicating a higher risk for adverse outcomes. - **Hydration status** assesses fluid balance, which is essential, especially in patients with febrile neutropenia, as appropriate hydration can prevent worsened renal function and support blood pressure maintenance. Fever and chills, while important indicators of infection, are included in the broader clinical picture rather than a specific quantitative measure like the MASCC index. Similarly, both complete blood