Advanced Oncology Certified Nurse Practitioner (AOCNP) Certification Practice Test

What percentage of SVC syndrome cases are associated with Diffuse Large B Cell Lymphoma and Lymphoblastic lymphoma?

1. 5-10%

2. 10-15%

3. 15-20%

4. 20-25%

The correct answer is: 10-15%

Diffuse Large B Cell Lymphoma (DLBCL) and Lymphoblastic lymphoma are both hematological malignancies that can lead to Superior Vena Cava (SVC) syndrome due to their potential to cause large masses in the mediastinum, which can compress the SVC. The percentage of SVC syndrome cases associated with these particular types of lymphoma, estimated to fall within the range of 10-15%, aligns with established clinical findings and epidemiological studies. This reflects the significant but not predominant role that these lymphomas play in causing the syndrome when compared to other malignancies like lung cancer or metastatic disease. Understanding this association is crucial for healthcare professionals in oncology and hematology, as it informs the clinical approach to diagnosing and managing patients with potential SVC syndrome. Recognizing the common lymphomas that lead to compression of the SVC allows for timely intervention, which can significantly impact patient outcomes.